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Live and let die: signaling AKTivation and UPRegulation dynamics in SARS-CoVs infection and cancer

3 Oct 2022

Abstract excerpt

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the coronavirus disease 2019 (COVID-19) pandemic. Of particular interest for this topic are the signaling cascades that regulate cell survival and death, two opposite cell programs whose control is hijacked by viral infections. The AKT and the Unfolded Protein Response (UPR) pathways, which maintain cell homeostasis...

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PMID: 36192392
DOI: 10.1038/s41419-022-05250-5

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