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Article

Somatic mutation variant analysis in rural, resectable non-small cell lung carcinoma patients.

Cancer genetics - 1 Nov 2022

Mitchem Jonathan B, Miller Amanda, Manjunath Yariswamy, Barbirou Mouadh, Raju Murugesan, Shen Yuanyuan, Li Guangfu, Avella Diego M, Chaudhuri Aadel A, Shyu Chi-Ren, Warren Wesley C, Tonellato Peter J, Kaifi Jussuf T

Abstract excerpt

Rural non-small cell lung cancer (NSCLC) patients do worse, largely related to lack of access to care. In this study, the mutational characteristics and potential for targeted therapy in rural, resectable NSCLC patients using whole exome sequencing (WES) were analyzed. WES was performed on tumor-adjacent normal pairs from rural patients undergoing resection for NSCLC. Sequencing alignment, variant-calling,...

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PMID: 36191390
DOI: 10.1016/j.cancergen.2022.09.008

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