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Article

Prevalence of Genomic Alterations in EGFR, KRAS, NRAS, and BRAF Among Early-Stage Nonsquamous Non-Small Cell Lung Cancer in Brazil.

JCO global oncology - 1 Jan 2026

Marques Fabiana Kalina, Barbosa de Carvalho André Henrique, Cordeiro de Lima Vladmir Cláudio, Siqueira Roberto Jacqueline, Menezes Freire Maira Cristina

Abstract excerpt

PURPOSE: We studied the prevalence of somatic mutations in EGFR, KRAS, BRAF, and NRAS among Brazilian patients with early-stage non-small cell lung cancer (NSCLC). We also explored the association between these mutations and clinicopathologic characteristics. METHODS: We screened 557 patients diagnosed with NSCLC who underwent EGFR, KRAS, BRAF, and NRAS gene sequencing by next-generation sequencing (NGS) or...

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Identifiers

PMID: 41538756
DOI: 10.1200/GO-25-00231

Genes

EGFR
KRAS
BRAF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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