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Article

Genomic alterations predictive of poor clinical outcomes in pan-cancer.

Oncotarget - 1 Jan 2022

Seldon Crystal S, Meiyappan Karthik, Hoffman Hannah, Guo Jimmy A, Goel Neha, Hwang William L, Nguyen Paul L, Mahal Brandon A, Alshalalfa Mohammed

Abstract excerpt

BACKGROUND: Genomic alterations are highly frequent across cancers, but their prognostic impact is not well characterized in pan-cancer cohorts. Here, we use pan-cancer cohorts from TCGA and MSK-IMPACT to evaluate the associations of common genomic alterations with poor clinical outcome. MATERIALS AND METHODS: Genomic alterations in commonly altered genes were extracted from Pan-Cancer TCGA and MSK-IMPACT...

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Identifiers

PMID: 36187555
DOI: 10.18632/oncotarget.28276
PMCID: PMC9518688

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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