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Article

Pan-Cancer Molecular Biomarkers: A Paradigm Shift in Diagnostic Pathology.

Surgical pathology clinics - 1 Sept 2021

Dong Fei

Abstract excerpt

The rapid adoption of next-generation sequencing in clinical oncology has enabled the detection of molecular biomarkers shared between multiple tumor types. These pan-cancer biomarkers include sequence-altering mutations, copy number changes, gene rearrangements, and mutational signatures and have been demonstrated to predict response to targeted therapy. This article reviews issues surrounding current and...

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Identifiers

PMID: 34373099
DOI: 10.1016/j.path.2021.05.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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