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Article

Energy balance-related factors in childhood and adolescence and risk of colorectal cancer based on KRAS, PIK3CA, and BRAF mutations and MMR status.

Molecular carcinogenesis - 1 Dec 2022

Jenniskens Josien C A, Offermans Kelly, Simons Colinda C J M, Samarska Iryna, Fazzi Gregorio E, van der Meer Jaleesa R M, Smits Kim M, Schouten Leo J, Weijenberg Matty P, Grabsch Heike I, van den Brandt Piet A

Abstract excerpt

KRAS mutations (KRASmut ), PIK3CAmut , BRAFmut , and deficient DNA mismatch repair (dMMR) have been associated with the Warburg effect. We previously reported differential associations between early-life energy balance-related factors (height, energy restriction, body mass index [BMI]) and colorectal cancer (CRC) subtypes based on the Warburg effect. We now investigated associations of early-life energy...

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Identifiers

PMID: 36177801
DOI: 10.1002/mc.23459
PMCID: PMC9828509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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