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Article

Early Life Exposure to Famine and Colorectal Cancer Risk: A Role for Epigenetic Mechanisms

20 Nov 2009

Abstract excerpt

BACKGROUND: Exposure to energy restriction during childhood and adolescence is associated with a lower risk of developing colorectal cancer (CRC). Epigenetic dysregulation during this critical period of growth and development may be a mechanism to explain such observations. Within the Netherlands Cohort Study on diet and cancer, we investigated the association between early life energy restriction and risk of...

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PMID: 19956740
DOI: 10.1371/journal.pone.0007951

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