Article
Hereditary cancer and developmental abnormalities.
Biology of the neonate - 1 Jan 2000
Ben-Yosef T, Benvenisty N
Abstract excerpt
About 1% of all cancers are hereditary, caused by germ-line mutations in specific cancer-related genes. More than 25 different hereditary cancer syndromes are known, most of them involving mutations in tumor suppressor genes. These genes, which are related to cellular proliferation, might also be involved in differentiation. Hence, the phenotype of hereditary cancer syndromes might include developmental...
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