Article
Euonymine inhibits in-stent restenosis through enhancing contractile phenotype of vascular smooth muscle cells via modulating the PTEN/AKT/mTOR signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology - 1 Dec 2022
Zhang Li, Tao YiTing, Yang RenHua, Hu Qin, Jia Jia, Yu MingYang, He Bo, Shen ZhiQiang, Qin HongTao, Yu Zhuo, Chen Peng
Abstract excerpt
BACKGROUND: Percutaneous coronary intervention (PCI) is an effective treatment for acute myocardial infarction, but the postoperative in-stent re-stenosis (ISR) remains a major risk factor that affects the prognosis of PCI. Clinically, drug-eluting stents (DES) are widely applied to prevent and treat ISR. However, only a few stent coating drugs are currently available for clinical use, including paclitaxel and...
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