Article
Post-treatment symptomatic improvement of the eastern Indian ADHD probands is influenced by CYP2D6 genetic variations.
Drug metabolism and personalized therapy - 1 Mar 2023
Chatterjee Mahasweta, Saha Sharmistha, Maitra Subhamita, Ray Anirban, Sinha Swagata, Mukhopadhyay Kanchan
Abstract excerpt
OBJECTIVES: Symptomatic remediation from attention deficit hyperactivity disorder (ADHD)-associated traits is achieved by treatment with methylphenidate (MPH)/atomoxetine (ATX). We have analyzed the association of functional CYP2D6 variations, rs1065852, rs3892097, rs1135840, and rs1058164, with ADHD in the Indian subjects. METHODS: Subjects were recruited following the Diagnostic and Statistical Manual for...
Read the complete abstract on PubMed