Article
Genetic analysis of the aquaporin water channels AQP12A and AQP12B in patients with chronic pancreatitis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Dec 2022
Eiseler Katharina, Dropmann Lea Maria, Bugert Peter, Ewers Maren, Witt Heiko
Abstract excerpt
BACKGROUND: Alterations in genes specifically expressed in the pancreas have been associated with chronic pancreatitis (CP). A significant percentage of patients with non-alcoholic CP, however, do not have mutations in known risk genes, suggesting the existence of further susceptibility genes. Four aquaporins are expressed in the exocrine pancreas: AQP1, AQP5, AQP8 and AQP12, the latter being found exclusively in...
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