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Article

Oxidative stress‐induced lncRNA CYLD‐AS1 promotes RPE inflammation via Nrf2/ miR ‐134‐5p/ NF‐κB signaling pathway

27 Sept 2022

Abstract excerpt

Abstract Oxidative stress‐induced damage to and dysfunction of retinal pigment epithelium (RPE) cells are important pathogenetic factors of age‐related macular degeneration (AMD); however, the underlying molecular mechanism is not fully understood. Long noncoding RNAs (lncRNAs) have important roles in various biological processes. In this study, using an oxidative damage model in RPE cells, we identified a novel...

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PMID: 36165267
DOI: 10.1096/fj.202200887r

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