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Article

Contribution of HLA class II genes, DRB401:01, DRB107:01, and DQB1*03:03:2 to clinical features of Vitiligo disease in Iranian population.

Molecular biology reports - 1 Jan 2022

Ghaffarnia Roya, Saffarian Zahra, Shahbazi Majid, Zamani Mahdi

Abstract excerpt

BACKGROUND: Vitiligo is a multifactorial depigmentation condition, which is due to skin melanocyte destruction. Increased expression of HLA class II genes in patients with pre-lesions of Vitiligo suggests a crucial role for the participation of immune response in Vitiligo development. Recent studies progressively focused on HLA-DRB1 and DQB1 genes. In this study, we have evaluated the association and role of...

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PMID: 34686989
DOI: 10.1007/s11033-021-06855-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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