Article
Sex-Specific Associations Between Susceptibility to Mycobacterium avium Complex Lung Disease and Programmed Cell Death 1 Gene Polymorphisms.
The Journal of infectious diseases - 28 Jun 2023
Pan Sheng-Wei, Feng Jia-Yih, Wu Lawrence Shih-Hsin, Shu Chin-Chung, Wang Ping-Huai, Wang Jann-Yuan, Wang Hao-Chien, Su Wei-Juin, Chen Yuh-Min, Yu Chong-Jen
Abstract excerpt
BACKGROUND: Mycobacterium avium complex lung disease (MAC-LD) preferentially occurs in postmenopausal women and may have immune exhaustion involving the programmed cell death 1 (PD-1) pathway. It is still unknown whether sex-specific associations between susceptibility to MAC-LD and programmed cell death 1 gene (PDCD1) polymorphisms exist. METHODS: Adult patients with MAC-LD (n = 152) and controls (n = 167) were...
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