Article
Familial pulmonary Mycobacterium avium complex disease.
American journal of respiratory and critical care medicine - 1 May 2000
Tanaka E, Kimoto T, Matsumoto H, Tsuyuguchi K, Suzuki K, Nagai S, Shimadzu M, Ishibatake H, Murayama T, Amitani R
Abstract excerpt
We report two Japanese families affected by pulmonary Mycobacterium avium complex (MAC) disease, involving an older brother and younger sister in one family and two brothers in the second family. We investigated whether defects in the natural resistance-associated macrophage protein gene (NRAMP1) underlay susceptibility to MAC in these cases. All of the patients had computed tomographic findings of peripheral...
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