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DNA damage response signaling: A common link between cancer and cardiovascular diseases

26 Sept 2022

Abstract excerpt

DNA damage response (DDR) signaling ensures genomic and proteomic homeostasis to maintain a healthy genome. Dysregulation either in the form of down- or upregulation in the DDR pathways correlates with various pathophysiological states, including cancer and cardiovascular diseases (CVDs). Impaired DDR is studied as a signature mechanism for cancer; however, it also plays a role in ischemia-reperfusion injury...

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PMID: 36156462
DOI: 10.1002/cam4.5274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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