Article
The long noncoding RNA uc003pxg.1 interacts with miR-339-5p to promote TGF-β1 expression and vascular endothelial cell proliferation, migration and angiogenesis in coronary heart disease
2023-03-29
Abstract excerpt
This study aims to investigate the roles of lncRNA uc003pxg.1 and miR-339-5p in regulating the proliferation, migration and angiogenesis of vascular endothelial cells and affect the occurrence and development of coronary heart disease (CHD). First, the expression levels of uc003pxg.1 and miR-339-5p were verified in clinical samples, and the correlation between them was analyzed. Then, the target gene was identifie...
Topics
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- Blood Coagulation and Thrombosis Mechanisms
- Cancer-related molecular mechanisms research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Pregnancy and preeclampsia studies
- RNA modifications and cancer
Identifiers and source
- Literature Corpus work
- 253c09ae-314e-5b6a-979c-5d86e0f43edd
- DOI
- 10.21203/rs.3.rs-2739837/v1
