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Article

Allelic ROBO3 heterogeneity in Tunisian patients with horizontal gaze palsy with progressive scoliosis.

Journal of molecular neuroscience : MN - 1 Nov 2009

Amouri Rim, Nehdi Houda, Bouhlal Yosr, Kefi Mounir, Larnaout Abdelmajid, Hentati Fayçal

Abstract excerpt

Horizontal gaze palsy with progressive scoliosis (HGPPS) is a rare autosomal recessive disorder characterized by the congenital absence of horizontal gaze, progressive scoliosis, and failure of the corticospinal and somatosensory axon tracts to decussate in the medulla. HGPPS is caused by mutations of the ROBO3 gene, which encodes a protein that shares homology with the roundabout family of transmembrane...

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Source

Identifiers

PMID: 19633821
DOI: 10.1007/s12031-009-9217-4

Genes

ROBO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Allelic ROBO3 heterogeneity in Tunisian patients with horizontal gaze palsy with progressive scoliosis.PMID 19633821Read ↗

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Horizontal gaze palsy with progressive scoliosis: Further expanding the ROBO3 spectrum.Semantic proximity Read ↗

Horizontal gaze palsy with progressive scoliosis: three novel ROBO3 mutations and descriptions of the phenotypes of four patients.Semantic proximity Read ↗

Horizontal gaze palsy and progressive scoliosis without ROBO3 mutations.Semantic proximity Read ↗

Horizontal gaze palsy with progressive scoliosis can result from compound heterozygous mutations in ROBO3.Semantic proximity Read ↗

Five new consanguineous families with horizontal gaze palsy and progressive scoliosis and novel ROBO3 mutations.Semantic proximity Read ↗

Horizontal gaze palsy with progressive scoliosis (HGPPS): expanding ROBO3 molecular spectrum and refining clinical-neuroimaging phenotypes.Semantic proximity Read ↗

Horizontal gaze palsy and progressive scoliosis due to a deleterious mutation in ROBO3.Semantic proximity Read ↗

Neurologic features of horizontal gaze palsy and progressive scoliosis with mutations in ROBO3.Semantic proximity Read ↗

A novel mutation of ROBO3 in horizontal gaze palsy with progressive scoliosis.Semantic proximity Read ↗

Early-onset or rapidly progressive scoliosis in children: check the eyes!Semantic proximity Read ↗

Horizontal gaze palsy and progressive scoliosis-a tale of two siblings with ROBO3 mutation.Semantic proximity Read ↗

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