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Article

Analysis of the Contribution of Intrinsic Disorder in Shaping Potyvirus Genetic Diversity.

Viruses - 3 Sept 2022

Lafforgue Guillaume, Michon Thierry, Charon Justine

Abstract excerpt

Intrinsically disordered regions (IDRs) are abundant in the proteome of RNA viruses. The multifunctional properties of these regions are widely documented and their structural flexibility is associated with the low constraint in their amino acid positions. Therefore, from an evolutionary stand point, these regions could have a greater propensity to accumulate non-synonymous mutations (NS) than highly structured...

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PMID: 36146764
DOI: 10.3390/v14091959
PMCID: PMC9504506

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