Article
Genetic Association of Beta-Myosin Heavy-Chain Gene (MYH7) with Cardiac Dysfunction.
Genes - 29 Aug 2022
Yousaf Memoona, Khan Waqas Ahmed, Shahzad Khurrum, Khan Haq Nawaz, Ali Basharat, Hussain Misbah, Awan Fazli Rabbi, Mustafa Hamid, Sheikh Farah Nadia
Abstract excerpt
Cardiac dysfunction accelerates the risk of heart failure, and its pathogenesis involves a complex interaction between genetic and environmental factors. Variations in myosin affect contractile abilities of cardiomyocytes and cause structural and functional abnormalities in myocardium. The study aims to find the association of MYH7 rs121913642 (c.1594 T>C) and rs121913645 (c.667G>A) variants with cardiac...
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