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[Analyzing the clinical phenotype of heart disease caused by the double mutation of p.Gly743Arg and p.Glu1389Lys carrying the myosin heavy chain gene].

Zhonghua wei zhong bing ji jiu yi xue - 1 Nov 2021

Zhong Shenghan, Wang Yao, Chen Wei, Wei Jiangjun, Fang Qinghua, Long Xianglin, He Jiacheng, Deng Songbai, She Qiang, Du Jianlin

Abstract excerpt

OBJECTIVE: To investigate the relationship between double mutations of myosin heavy chain gene (MYH6) p.Gly743Arg and p.Glu1389Lys and the cardiac phenotype. METHODS: Patients carrying double mutations in the MYH6 gene p.Gly743Arg and p.Glu1389Lys were screened from 52 unrelated left ventricular hypertrophy (LVH) who were admitted to the Second Hospital of Chongqing Medical University from 2015 to 2020, and the...

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PMID: 34980302
DOI: 10.3760/cma.j.cn121430-20210602-00817

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