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Article

Variation p.R1045H in MYH7 correlated with hypertrophic cardiomyopathy in a Chinese pedigree.

BMC medical genomics - 30 Jul 2021

Zhang Yan, Shang Yiyi, Liu Luo, Ding Xiaoxue, Wu Haiyan, Li Lijiang, Pang Mingjie

Abstract excerpt

BACKGROUND: Inherited hypertrophic cardiomyopathy (HCM) is a common heart muscle disease that damages heart function and may cause the heart to suddenly stop beating. Genetic factors play an important role in HCM. Pedigree analysis is a good way to identify the genetic defects that cause disease. METHODS: An HCM pedigree was determined in Yunnan, China. Whole-exome sequencing was performed to identify the genetic...

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Identifiers

PMID: 34330286
DOI: 10.1186/s12920-021-01046-2
PMCID: PMC8325323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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