Article
Incidence of Germline Variants in Familial Bladder Cancer and Among Patients With Cancer Predisposition Syndromes.
Clinical genitourinary cancer - 1 Dec 2022
Mossanen Matthew, Nassar Amin H, Stokes Samantha M, Martinez-Chanza Nieves, Kumar Vivek, Nuzzo Pier Vitale, Kwiatkowski David J, Garber Judy E, Curran Catherine, Freeman Dory, Preston Mark, Mouw Kent W, Kibel Adam, Choueiri Toni K, Sonpavde Guru, Rana Huma Q
Abstract excerpt
BACKGROUND: The familial aggregation of bladder cancers has been observed, but the incidence and association of familial bladder cancer with germline pathogenic and likely pathogenic (P/LP) variants is unknown. PATIENTS AND METHODS: A retrospective analysis was conducted of patients with bladder cancer treated at the Dana-Farber Cancer Institute to identify those with a first-degree relative with bladder cancer....
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