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Article

Structural ECM components in the premetastatic and metastatic niche

7 Apr 2016

Abstract excerpt

The aim of this review is to give an overview of the extracellular matrix (ECM) components that are important for creating structural changes in the premetastatic and metastatic niche. The successful arrival and survival of cancer cells that have left the primary tumor and colonized distant sites depends on the new microenvironment they encounter. The primary tumor itself releases factors into the circulation...

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PMID: 27053524
DOI: 10.1152/ajpcell.00326.2015

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