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Article

Variants influencing age at diagnosis of HNF1A-MODY.

Molecular medicine (Cambridge, Mass.) - 14 Sept 2022

Ludwig-Słomczyńska Agnieszka H, Seweryn Michał T, Radkowski Piotr, Kapusta Przemysław, Machlowska Julita, Pruhova Stepanka, Gasperikova Daniela, Bellanne-Chantelot Christine, Hattersley Andrew, Kandasamy Balamurugan, Letourneau-Freiberg Lisa, Philipson Louis, Doria Alessandro, Wołkow Paweł P, Małecki Maciej T, Klupa Tomasz

Abstract excerpt

BACKGROUND: HNF1A-MODY is a monogenic form of diabetes caused by variants in the HNF1A gene. Different HNF1A variants are associated with differences in age of disease onset, but other factors are postulated to influence this trait. Here, we searched for genetic variants influencing age of HNF1A-MODY onset. METHODS: Blood samples from 843 HNF1A-MODY patients from Czech Republic, France, Poland, Slovakia, the UK...

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Identifiers

PMID: 36104811
DOI: 10.1186/s10020-022-00542-0
PMCID: PMC9476297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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