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Article

GCK and HNF1A mutations in Canadian families with maturity onset diabetes of the young (MODY).

Human mutation - 1 Dec 2002

Cao Henian, Shorey Sanam, Robinson John, Metzger Daniel L, Stewart Laura, Cummings Elizabeth, Hegele Robert A

Abstract excerpt

Maturity onset diabetes of the young (MODY) is a genetically heterogeneous form of type 2 diabetes that is characterized by autosomal dominant inheritance, onset in early adulthood and a primary defect in insulin secretion. Mutations in at least six genes have been shown to underlie MODY, including mutations in GCK (encoding glucokinase, also called MODY2) and mutations in HNF1A (encoding hepatocyte nuclear...

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Source

Identifiers

PMID: 12442280
DOI: 10.1002/humu.9090

Genes

GCK

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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