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Article

Polymorphism of IL-1B rs16944 (T/C) associated with serum levels of IL-1β affects seizure susceptibility in ischemic stroke patients.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Jan 2023

Ma Xiaojun, Sun Liangwei, Li Xiaoli, Xu Yanlu, Zhang Qingyan

Abstract excerpt

BACKGROUND: Seizures and the subsequent development of epilepsy after stroke may not only hinder patient's recovery but also increase the risk of complications. Interleukin (IL)-1β has been shown to be acutely upregulated after ischemic stroke and play a role in the recurrence of seizures following the first epileptic seizure in patients suffering an ischemic stroke. Meanwhile, variants of the IL-1B gene encoding...

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PMID: 36089763
DOI: 10.17219/acem/152738

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