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Article

IL-1β associations with posttraumatic epilepsy development: a genetics and biomarker cohort study.

Epilepsia - 1 Jul 2014

Diamond Matthew L, Ritter Anne C, Failla Michelle D, Boles Jennifer A, Conley Yvette P, Kochanek Patrick M, Wagner Amy K

Abstract excerpt

OBJECTIVE: Posttraumatic epilepsy (PTE) is a significant complication following traumatic brain injury (TBI), yet the role of genetic variation in modulating PTE onset is unclear. We hypothesized that TBI-induced inflammation likely contributes to seizure development. We assessed whether genetic variation in the interleukin-1beta (IL-1β) gene, IL-1β levels in cerebrospinal fluid (CSF) and serum, and CSF/serum...

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Identifiers

PMID: 24754437
DOI: 10.1111/epi.12628
PMCID: PMC4107119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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