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Article

Single nucleotide polymorphism and production of IL-1β and IL-10 cytokines in febrile seizures.

Neuropediatrics - 1 Aug 2012

Nur B G, Sahinturk D, Coskun M, Duman O, Yavuzer U, Haspolat S

Abstract excerpt

Inflammation and genetics may play a role in the pathogenesis of febrile seizures. The aim of this study was to investigate the spontaneous and lipopolysaccharide (LPS)-induced production of IL-1β and IL-10, and the association between IL-1β (-511) and IL-10 (-1082) single nucleotide polymorphisms with LPS-induced cytokine production. The study included 92 febrile seizure patients and 132 healthy controls. First,...

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PMID: 22911481
DOI: 10.1055/s-0032-1323849

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