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Article

Functional polymorphism rs3783553 in the 3'-untranslated region of IL-1A increased the risk of ischemic stroke: A case-control study.

Medicine - 1 Nov 2017

Wang Peng, He Qian, Liu Chen, He Shi Zhen, Zhu Shou Yan, Li Ying Wen, Su Wei, Xiang Shu Tian, Zhao Bo

Abstract excerpt

Accumulating evidence indicates interleukin-1 (IL-1) is a critical mediator of inflammatory responses in ischemic stroke (IS). The aim of this study was to investigate whether rs3783553 in the 3'-untranslated region of IL-1A was associated with the risk of IS. In this hospital-based case-control study, we genotyped the rs3783553 using polymerase chain reaction in 316 patients with IS and 332 age, sex, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29145255
DOI: 10.1097/MD.0000000000008522
PMCID: PMC5704800

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