Article
Joint effects of febrile acute infection and an interferon-γ polymorphism on breast cancer risk.
PloS one - 1 Jan 2012
Su Yi, Tang Lu-Ying, Chen Li-Juan, He Jian-Rong, Su Feng-Xi, Lin Ying, Chen Wei-Qing, Xie Xiao-Ming, Ren Ze-Fang
Abstract excerpt
BACKGROUND: There is an inverse relationship between febrile infection and the risk of malignancies. Interferon gamma (IFN-γ) plays an important role in fever induction and its expression increases with incubation at fever-range temperatures. Therefore, the genetic polymorphism of IFN-γ may modif...
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