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Associations between cytokine genes and a symptom cluster of pain, fatigue, sleep disturbance, and depression in patients prior to breast cancer surgery.

Biological research for nursing - 1 May 2015

Doong Sy-Huey, Dhruva Anand, Dunn Laura B, West Claudia, Paul Steven M, Cooper Bruce A, Elboim Charles, Abrams Gary, Merriman John D, Langford Dale J, Leutwyler Heather, Baggott Christina, Kober Kord, Aouizerat Bradley E, Miaskowski Christine

Abstract excerpt

Pain, fatigue, sleep disturbance, and depression are common and frequently co-occurring symptoms in oncology patients. This symptom cluster is often attributed to the release of proinflammatory cytokines. The purposes of this study were to determine whether distinct latent classes of patients with breast cancer (n = 398) could be identified based on their experience with this symptom cluster, whether patients in...

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PMID: 25304131
DOI: 10.1177/1099800414550394
PMCID: PMC5486211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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