Article
Next-generation sequencing in salivary gland carcinoma: Targetable alterations lead to a therapeutic advantage-Multicenter experience.
Head & neck - 1 Apr 2020
Moore Assaf, Bar Yael, Maurice-Dror Corinne, Ospovat Inna, Sarfaty Michal, Korzets Yasmin, Goldvaser Hadar, Gordon Noa, Billan Salem, Gutfeld Orit, Popovtzer Aron
Abstract excerpt
BACKGROUND: Salivary gland cancers (SGCs) are rare. The approach to metastatic patients is histology-dependent. There is little evidence on whether next-generation sequencing (NGS) findings translate to tumor control in SGCs. METHODS: We analyzed all patients with histologically confirmed SGC who underwent NGS. RESULTS: Twenty-seven patients were identified, 14 (51.8%) had targetable findings in NGS: 5 ERBB2...
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