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Article

Topographical Distribution and Phenotype of Resident Meibomian Gland Orifice Immune Cells (MOICs) in Mice and the Effects of Topical Benzalkonium Chloride (BAK).

International journal of molecular sciences - 24 Aug 2022

Wu Ching Yi, Wu Mengliang, Huang Xin, Gu Ben J, Maldonado-Codina Carole, Morgan Philip B, Downie Laura E, Chinnery Holly R

Abstract excerpt

Meibomian gland orifices (MGOs) are located along the eyelid margin and secrete meibum into the tear film. The profile of resident innate immune cells (ICs) at this site is not well understood. The distribution and phenotype of resident ICs around MGOs in mice was investigated and herein defined as MGO-associated immune cells (MOICs). The effect of topical 0.1% benzalkonium chloride (BAK) on MOICs was also...

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PMID: 36077001
DOI: 10.3390/ijms23179589
PMCID: PMC9455816

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