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Article

Immunosuppressant exposure confounds gene expression analysis in systemic lupus erythematosus

17 Aug 2022

Abstract excerpt

Objectives: The analysis of gene module expression in SLE is emerging as a tool to identify active biological pathways, with the aim of developing targeted therapies for subsets of patients. Detailed information on the effect of immunosuppressants on gene module expression is lacking. We aimed to examine the impact of medication exposure on gene module expression. Methods: A set of commercially available...

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PMID: 36059457
DOI: 10.3389/fimmu.2022.964263

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