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Article

ImaGene: a convolutional neural network to quantify natural selection from genomic data.

BMC bioinformatics - 22 Nov 2019

Torada Luis, Lorenzon Lucrezia, Beddis Alice, Isildak Ulas, Pattini Linda, Mathieson Sara, Fumagalli Matteo

Abstract excerpt

BACKGROUND: The genetic bases of many complex phenotypes are still largely unknown, mostly due to the polygenic nature of the traits and the small effect of each associated mutation. An alternative approach to classic association studies to determining such genetic bases is an evolutionary framework. As sites targeted by natural selection are likely to harbor important functionalities for the carrier, the...

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Identifiers

PMID: 31757205
DOI: 10.1186/s12859-019-2927-x
PMCID: PMC6873651

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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