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Article

ECT2 overexpression promotes the polarization of tumor-associated macrophages in hepatocellular carcinoma via the ECT2/PLK1/PTEN pathway.

Cell death & disease - 8 Feb 2021

Xu Dafeng, Wang Yu, Wu Jincai, Zhang Zhensheng, Chen Jiacheng, Xie Mingwei, Tang Rong, Chen Cheng, Chen Liang, Lin Shixun, Luo Xiangxiang, Zheng Jinfang

Abstract excerpt

Hepatocellular carcinoma (HCC) is a common high-mortality cancer, mainly due to diagnostic difficulties during its early clinical stages. In this study, we aimed to identify genes that are important for HCC diagnosis and treatment, and we investigated the underlying mechanism of prognostic differences. Differentially expressed genes (DEGs) were identified by using the limma package, and receiver operating...

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Identifiers

PMID: 33558466
DOI: 10.1038/s41419-021-03450-z
PMCID: PMC7870664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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