Article

Pathway and network embedding methods for prioritizing psychiatric drugs

2019-08-13

Abstract excerpt

One in five Americans experience mental illness, and roughly 75% of psychiatric prescriptions do not successfully treat the patient’s condition. Extensive evidence implicates genetic factors and signaling disruption in the pathophysiology of these diseases. Changes in transcription often underlie this molecular pathway dysregulation; individual patient transcriptional data can improve the efficacy of diagnosis and...

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Literature Corpus work: bf8ff2ec-e812-5bfc-81dd-5ebcfaad94d5
DOI: 10.1101/728055

Open publication

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