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The Risk of Emerging Resistance to Trimethoprim/Sulfamethoxazole in Staphylococcus aureus

1 Aug 2022

Abstract excerpt

Objective: Due to the spread of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), the demand for trimethoprim/sulfamethoxazole (SXT) is increasing in the world. It is not clear whether the resistant strain emerges by overuse of SXT. We investigated here the emergent risk of the SXT-resistant mutant in S. aureus by an in vitro SXT exposure experiment. Methods: A total of 40 S. aureus...

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PMID: 36039323
DOI: 10.2147/idr.s375588

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