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Article

Phenotypic Detection of Hemin-Inducible Trimethoprim-Sulfamethoxazole Heteroresistance in Staphylococcus aureus.

Microbiology spectrum - 31 Oct 2021

Nurjadi Dennis, Chanthalangsy Quan, Zizmann Elfi, Stuermer Vanessa, Moll Maximilian, Klein Sabrina, Boutin Sébastien, Heeg Klaus, Zanger Philipp

Abstract excerpt

Trimethoprim-sulfamethoxazole (SXT) is a valuable second-line antimicrobial agent to treat methicillin-resistant Staphylococcus aureus infections. Discrepancies between various antibiotic susceptibility testing (AST) methods for SXT susceptibility in S. aureus have been described. Here, we describe a hemin-inducible heteroresistance phenotype in S. aureus. We compared the results of the Vitek 2 AST on a set of 95...

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Identifiers

PMID: 34704796
DOI: 10.1128/Spectrum.01510-21
PMCID: PMC8549745

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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