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Article

Cryobanking of Human Distal Lung Epithelial Cells for Preservation of Their Phenotypic and Functional Characteristics.

American journal of respiratory cell and molecular biology - 1 Dec 2022

Konda Bindu, Mulay Apoorva, Yao Changfu, Israely Edo, Beil Stephen, Huynh Carissa A, Tourtellotte Warren G, Rampolla Reinaldo, Chen Peter, Carraro Gianni, Stripp Barry R

Abstract excerpt

The epithelium lining airspaces of the human lung is maintained by regional stem cells, including basal cells of pseudostratified airways and alveolar type 2 (AT2) pneumocytes of the gas-exchange region. Despite effective techniques for long-term preservation of airway basal cells, procedures for efficient preservation of functional epithelial cell types of the distal gas-exchange region are lacking. Here we...

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PMID: 36036918
DOI: 10.1165/rcmb.2021-0507MA

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