Article
Polymorphism in alpha-synuclein oligomers and its implications in toxicity under disease conditions
12 Aug 2022
Abstract excerpt
The major hallmark of Parkinson's disease (PD) is represented by the formation of pathological protein plaques largely consisting of α-synuclein (αSN) amyloid fibrils. Nevertheless, the implications of αSN oligomers in neuronal impairments and disease progression are more importantly highlighted than mature fibrils, as they provoke more detrimental damages in neuronal cells and thereby exacerbate...
Topics
Join the communities discussing this publication.