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Article

Vγ9Vδ2 T-cells Are Potent Inhibitors of SARS-CoV-2 Replication and Represent Effector Phenotypes in Patients With COVID-19.

The Journal of infectious diseases - 14 Jun 2024

Gay Laetitia, Rouviere Marie-Sarah, Mezouar Soraya, Richaud Manon, Gorvel Laurent, Foucher Etienne, La Scola Bernard, Menard Amélie, Allardet-Servent Jérôme, Halfon Philippe, Frohna Paul, Cano Carla, Mege Jean-Louis, Olive Daniel

Abstract excerpt

Vγ9Vδ2 T cells play a key role in the innate immune response to viral infections through butyrophilin 3A (BTN3A). Here, we report blood Vγ9Vδ2 T cells decreased in clinically mild COVID-19 compared to healthy volunteers, and this was maintained up to 28 days and in the recovery period. Terminally differentiated Vγ9Vδ2 T cells tended to be enriched on the day of diagnosis, 28 days after, and during the recovery...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38557809
DOI: 10.1093/infdis/jiae169

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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