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The Effects of Tamoxifen on Tolerogenic Cells in Cancer

17 Aug 2022

Abstract excerpt

Tamoxifen (TAM) is the most prescribed selective estrogen receptor modulator (SERM) to treat hormone-receptor-positive breast cancer patients and has been used for more than 20 years. Its role as a hormone therapy is well established; however, the potential role in modulating tolerogenic cells needs to be better clarified. Infiltrating tumor-microenvironment-regulatory T cells (TME-Tregs) are important as they...

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PMID: 36009853
DOI: 10.3390/biology11081225

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