Article
The molecular genetics of human facioscapulohumeral muscular dystrophy and the myodystrophy mouse model.
Current opinion in neurology - 1 Oct 1996
Mathews K D, Mills K A
Abstract excerpt
Facioscapulohumeral dystrophy is an autosomal dominant muscular dystrophy, the gene for which is localized to 4q35. It appears to be caused by deletion of tandem repeats that do not contain an expressed sequence. One current hypothesis is that the deletion affects expression of a centromeric gene...
Topics
- Animals
- Child
- Chromosome Mapping
- Chromosomes, Human, Pair 10
- Chromosomes, Human, Pair 4
- Chromosomes, Human, Pair 8
- Disease Models, Animal
- Gene Expression Regulation
- Humans
- Mice
- Muscular Dystrophies
- Muscular Dystrophy, Animal
- Phenotype