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Article

Novel polymorphism of the HMGCR gene related to the risk of diabetes in premature triple-vessel disease patients.

The journal of gene medicine - 1 Sept 2022

Zhao Xueyan, Tang Xiaofang, Xu Jingjing, Liu Ru, Huang Keyong, Li Jiawen, Li Yulong, Jiang Lin, Xu Lianjun, Zhang Yin, Wang Dong, Hui Rutai, Gao Runlin, Song Lei, Yuan Jinqing

Abstract excerpt

BACKGROUND: Coronary heart disease and diabetes are highly interrelated and complex diseases. We proposed to investigate the association of genetic polymorphisms of the lipoprotein important regulatory genes Niemann-Pick C1-like 1 (NPC1L1) and 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) in patients with premature triple-vessel coronary disease (PTVD) with diabetes, blood glucose and body mass index....

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Identifiers

PMID: 35998373
DOI: 10.1002/jgm.3445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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