Article
MassARRAY multigene screening combined with LDL-C and sdLDL-C detection for more favorable outcomes in type 2 diabetes mellitus therapy.
BMC medical genomics - 17 Mar 2021
Tian Yong, Wang Junhong, Liu Yanxiao, Luo Xiangguang, Yao Ziying, Wang Xinjun, Zhang Yuanyuan, Xu Cheng, Zhao Xiaoyu
Abstract excerpt
BACKGROUND: To determine the clinical value of multigene polymorphisms, LDL-C and sdLDL-C on T2DM therapy. METHODS: In total, 352 T2DM patients before and after treatment and 48 healthy individuals were enrolled in this study. LDL-C and sdLDL-C were detected in 352 T2DM patients and 48 healthy individuals by Quantimetrix Lipoprint System. The 11 gene polymorphisms-HTR3B (rs2276307, A > G), APOE (rs7412,...
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