Article
Causal Association of Thyroid Signaling with C-Reactive Protein: A Bidirectional Mendelian Randomization.
Computational and mathematical methods in medicine - 1 Jan 2022
Li Tingting, Geng Haigang, Wang Yuquan, Wu Zhaorong, Yang Siqian, Hu Yue-Qing
Abstract excerpt
Methods: Based on the latest genome-wide association study summary data, bidirectional two-sample Mendelian randomization (MR) was employed to detect the causal relationship and effect direction between TSH, fT4, and CRP. Furthermore, in view of obesity being an important risk factor of CVD, obesity trait waist-hip ratio (WHR) and body mass index (BMI) were treated as the research objects in MR analyses for...
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