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Thyroid Function and Metabolic Syndrome: A Two-Sample Bidirectional Mendelian Randomization Study

19 Jun 2023

Abstract excerpt

CONTEXT: Thyroid function has been associated with metabolic syndrome (MetS) in a number of observational studies but the direction of effects and the exact causal mechanism of this relationship is still unknown. OBJECTIVE: To examine genetically predicted effects of thyroid function on MetS risk and its components, and vice versa, using large-scale summary genetic association data. METHODS: We performed a...

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PMID: 37339283
DOI: 10.1210/clinem/dgad371

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