Article
Association of periconceptional folate supplements and FOLR1 and FOLR2 gene polymorphisms with risk of congenital heart disease in offspring: A hospital-based case-control study.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 28 Jan 2022
Song Xinli, Huang Peng, Wang Tingting, Zhang Senmao, Chen Letao, Qin Jiabi
Abstract excerpt
OBJECTIVES: Maternal periconceptional folic acid supplement is by far the most effective primary prevention strategy to reduce the incidence of congenital heart disease (CHD) in offspring. It was revealed that the underlying mechanisms are complex, including a combination of genetic and environmental factors. The purpose of this study is to investigate the association between periconceptional folic acid...
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